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PiY [Catalog # P025]
■ Chemical structure & Information
PiY (Pancreatic islet Yellow) is a pancreatic beta cell selective probe over alpha cell or acinar cell. Through i.v. injection of PiY into mouse tale vein, pancreatic islet was vividly visualized to facilitate the islet isolation
■ Cell Image
3D structure processed image of a pancreatic islet. The fluorescent images of PiY(red) and FITC-dextran (green) were taken using TRITC and FITC channels, respectively. DAPI(blue) stain shows nuclei. Scale bar=50mm
■ Related probes: TP-beta, PiF
■ Known Property
pancreatic beta cell probe
■ Application
Immunofluorescence and visualization of islets in pancreatic tissue by i.v. injection of mouse
■ Cell selectivity mechanism
Unknown
pancreatic beta cell probe
■ Application
Immunofluorescence and visualization of islets in pancreatic tissue by i.v. injection of mouse
■ Cell selectivity mechanism
Unknown
■ Reference
1.
Visualization and isolation of Langerhans islets by fluorescent probe PiY, Kang, N. Y.; Lee, S. C.; Park, S. J.; Ha, H. H.; Yun, S. W.; Kostromina, E.; Gustavsson, N.; Ali, Y.; Chandran, Y.; Chun, H. S.; Bae, M. A.; Ahn, J. H.; Han, W.; Radda, G. K.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl., 2013, 52, 8557-8560.
■ ORDER
International
USD 350 + VAT (10%) + Fedex delivery charge
In Korea
KRW 450,000 + VAT (10%)
100 nmol (dried form: equivalent to 1 mM / 100 µL)
■ Storage
① Delivery: Room Temperature
② Dried compound: 4°C or -20°C
③ Compound solution: 4°C or -20°C
■ General Use Guide
•
More than 1/100 dilution of 10mM of DMSO stock solution is essential
•
For biomedical use to avoid DMSO concentration higher than 1%.
•
Working concentrations for specific applications should be determined by the investigator.
•
It is recommended to use up the buffer diluted solution within one day. The compound may be decomposed or
precipitated out from buffer solution.
precipitated out from buffer solution.
■ Data sheet PDF file
PiY data sheet v0.2.pdf673.23KB